Stronger Cows. Healthier Herds. More Profit.
Backed by over 25 years of research at the University of Guelph, Immunity Technology is a world-leading genetic solution that helps you breed cows with naturally stronger immune systems.

  • Healthier cows with fewer cases of mastitis, metritis, and respiratory disease
  • Lower vet and treatment costs
  • Improved fertility and longevity, keeping cows in your herd longer
  • More profit, with gains that build every generation
    By monitoring immunity in your herd, you’re not just treating disease — you’re preventing it.

  • BOVINE TUBERCULOSIS

    Immunity+® & Bovine Tuberculosis (bTB)
    Bovine tuberculosis (bTB) is a chronic infectious disease caused by Mycobacterium bovis, with major economic consequences for affected dairy farms — even in countries where it’s rare. Costs can be extremely high due to culling, testing, movement restrictions, and trade losses.

    Estimated Cost of Bovine TB to a Dairy If Reactor Found:
    $2,000 to over $25,000+ per year, depending on:
    • Number of reactors
    • Testing frequency
    • Culling and compensation policy
    • Farm size and restrictions

    For an individual infected cow:
    • $1,500 to $3,500 economic impact per cow culled:
    • Includes lost milk production, cull value loss, delayed replacement, and disruption to herd structure.

    How Immunity+ helps fight Bovine TB:
    • Improved Cell-Mediated Immunity+ (CMI)
      • bTB is primarily controlled by cell-mediated Immunity+ (T-cells)
      • Cows with the Immunity+ trait tend to have stronger CMI responses
      • This means:
        • Better recognition and destruction of infected cells
        • Lower bacterial replication and spread
        • Reduced disease progression
      • In research, HIR animals have shown stronger T-cell responses, which are critical in managing diseases like bTB.
    • Greater Vaccine Response Potential
      • While there is no widely used bTB vaccine for cattle (due to diagnostic interference), HIR animals generally show better responses to vaccines.
      • This suggests that if a bTB vaccine becomes viable, Immunity+ animals would be more likely to mount a protective response.
    • Reduced Disease Burden & Transmission Risk
      • Even if exposed to M. bovis, Immunity+ cattle may:
        • Clear the infection more efficiently
        • Remain asymptomatic for longer
        • Be less likely to transmit the disease to others
    • This helps lower herd prevalence over time, particularly when combined with testing and culling programs.

    Summary: Semex’s Immunity+ is not a cure or vaccine for bovine tuberculosis, but it’s a proactive, genetic defense strategy. By breeding cattle with superior immune responses — especially in the area of cell-mediated Immunity+ — you're building a herd better equipped to resist and contain bTB and other major diseases.

    FIND OUT MORE
  • Incidence Rates Of Clinical Mastitis Among Canadian Holsteins Classified As High, Average, Or Low Immune Responders

  • Genetic Parameters For Natural Antibodies And Associations With Specific Antibody And Mastitis In Canadian Holsteins


  • DISEASES
    BIRD FLU – H5N1
    BOVINE LEUKOSIS
    BOVINE TUBERCULOSIS
    CALF DIARRHEA/SCOURS
    DIGITAL DERMATITIS
    DISPLACED ABOMASUM
    ENDOMETRITIS/METRITIS
    INTERDIGITAL HYPERPLASIA
    JOHNE'S DISEASE
    KETOSIS
    MASTITIS
    PNEUMONIA
    RETAINED PLACENTA

    IMMUNITY TECHNOLOGY
    Only from Semex Elevate® and Neogen®