Stronger Cows. Healthier Herds. More Profit.
Backed by over 25 years of research at the University of Guelph, Immunity Technology is a world-leading genetic solution that helps you breed cows with naturally stronger immune systems.

  • Healthier cows with fewer cases of mastitis, metritis, and respiratory disease
  • Lower vet and treatment costs
  • Improved fertility and longevity, keeping cows in your herd longer
  • More profit, with gains that build every generation
    By monitoring immunity in your herd, you’re not just treating disease — you’re preventing it.

  • JOHNE'S DISEASE

    Immunity+® & Johnes
    Johne’s disease (paratuberculosis) is a chronic, incurable bacterial infection in dairy cattle caused by Mycobacterium avium subspecies paratuberculosis (MAP). It's slow to show clinical signs, but causes significant economic losses, especially due to:

    Reduced milk production
    Premature culling
    Increased mortality
    Lower reproductive performance
    Diagnostic and control costs

    Estimated Cost of Johne’s Disease/Case:
    $200 to $500+ per year

    How Immunity+ Helps Fight Johne’s Disease
    • Stronger Cell-Mediated Immunity+ (CMI)
      • Johne’s is an intracellular bacterial infection, meaning it hides inside cells.
      • The cell-mediated immune response is the key defense, involving T-cells that detect and destroy infected cells.
      • Immunity+ animals have stronger CMI, making them:
        • Less likely to get infected
        • More capable of containing the infection
        • Slower to progress to clinical disease
    • Lower Susceptibility in Calves
      • Most Johne’s infections occur in young calves exposed to contaminated manure, colostrum, or milk.
      • Calves born to Immunity+ dams inherit stronger immune systems, making them:
        • Better able to resist early infection
        • Less likely to become long-term MAP shedders
    • Slower Disease Progression
      • In animals that do become infected, a high immune response can:
        • Delay the onset of clinical signs
        • Reduce the rate and amount of MAP shedding
        • Extend productive life and reduce premature culling
    • Supports Johne’s Control Programs
      • Herds using Immunity+ genetics over time build a more resilient population.
      • When combined with biosecurity, testing, and culling, Immunity+ helps:
        • Lower overall herd prevalence
        • Improve response to control efforts
        • Reduce hidden economic losses

    Summary: Immunity+ helps fight Johne’s disease by genetically enhancing the immune system — especially the cell-mediated response — giving cows a better chance to resist infection, contain MAP, and stay productive longer. It’s not a silver bullet, but it's a powerful tool when used as part of a complete Johne’s prevention program.

    FIND OUT MORE
  • Genetic Selection Of Cattle For Improved Immunity And Health

  • Are There Reproductive Implications When Dairy Cattle Are Genetically Selected For Improved Immunity?

  • Immunity+ Evidence Growing

  • The 3000 Cow High Immune Response (HIR) Genomics Project

  • Genetic Selection Of Cattle For Improved Immunity And Health

  • Bovine Mastitis: Frontiers In Immunogenetics

  • A Genome-wide Association Study Of Immune Response Traits In Canadian Holstein Cattle

  • Dairy Farmers Have A New Tool To Help Them Build A Healthier Herd

  • We Can Now Find The Best Immune Systems

  • Immunity+ Frequently Asked Questions - Version 1

  • Immunity+ Frequently Asked Questions - Version 2


  • DISEASES
    BIRD FLU – H5N1
    BOVINE LEUKOSIS
    BOVINE TUBERCULOSIS
    CALF DIARRHEA/SCOURS
    DIGITAL DERMATITIS
    DISPLACED ABOMASUM
    ENDOMETRITIS/METRITIS
    INTERDIGITAL HYPERPLASIA
    JOHNE'S DISEASE
    KETOSIS
    MASTITIS
    PNEUMONIA
    RETAINED PLACENTA

    IMMUNITY TECHNOLOGY
    Only from Semex Elevate® and Neogen®