Stronger Cows. Healthier Herds. More Profit.
Backed by over 25 years of research at the University of Guelph, Immunity Technology is a world-leading genetic solution that helps you breed cows with naturally stronger immune systems.

  • Healthier cows with fewer cases of mastitis, metritis, and respiratory disease
  • Lower vet and treatment costs
  • Improved fertility and longevity, keeping cows in your herd longer
  • More profit, with gains that build every generation
    By monitoring immunity in your herd, you’re not just treating disease — you’re preventing it.

  • RETAINED PLACENTA

    Immunity+® & Retained Placenta (RP)
    Retained placenta (RP) — when a cow fails to expel fetal membranes within 24 hours after calving — is a common and costly postpartum disorder in dairy herds. It’s often a gateway to other diseases, like metritis and endometritis, making its true cost higher than it appears.

    Estimated Cost of Retained Placenta/Case:
    $200 to $450+ per affected cow

    Costs vary depending on:
    • Onset of secondary infections (e.g., metritis)
    • Milk production loss
    • Treatment and labor

    How Immunity+ Helps Fight Retained Placenta (RP)
    • Stronger Immune Surveillance During Calving
      • Normal placental separation requires inflammatory signals and immune cell activity.
      • Cows with HIR have a more efficient and timely immune response, supporting:
        • Proper placental detachment
        • Clean uterine environment
        • Reduced chance of membrane retention
    • Lower Risk of Postpartum Uterine Infections
      • RP is often followed by bacterial contamination of the uterus, which can spiral into metritis or endometritis.
      • Immunity+ cows show:
        • Stronger defense against uterine pathogens
        • Fewer secondary infections
        • Reduced inflammation and faster healing
    • Better Transition Health
      • RP risk increases with:
        • Metabolic stress
        • Ketosis
        • Milk fever
      • Immunity+ animals have fewer transition cow diseases, reducing physiological stress and supporting better postpartum reproductive recovery.
      • Inflammation and immune regulation are central to the placenta releasing properly. Immunity+ cows have been shown to handle this process more effectively, reducing RP risk.
    • Improved Reproductive Longevity
      • RP can lead to:
        • Longer days open
        • Delayed breeding
        • Early culling
      • Immunity+ cows:
        • Get pregnant sooner
        • Require fewer reproductive treatments
        • Stay in the herd longer

    Summary: Semex’s Immunity+ helps fight retained placenta by breeding cows with stronger, more effective immune systems, enabling faster placental release, fewer postpartum infections, and better reproductive outcomes. It's a proactive, long-term solution to improving transition cow health and fertility.

    FIND OUT MORE
  • Immune Classification And Colostral Quality

  • Genetic Selection Of Cattle For Improved Immunity And Health

  • Genetic And Epigenetic Regulation Of The Bovine Immune System: Practical Implications Of The High Immune Response Technology

  • Genetic Regulation Of The Bovine Immune System And The Practical Application Of The High Immune Response Technology In Dairy Health Management

  • The Use Of High Immune Response Bulls In A Herd

  • A Genome-wide Association Study Of Immune Response In Holstein Bulls

  • Genetic And Epigenetic Effects On Bovine Immune Responses And Their Implications To Dairy Health

  • Genetic Selection Of Cattle For Improved Immunity And Health

  • Immunity+ Frequently Asked Questions - Version 1

  • Immunity+ Frequently Asked Questions - Version 2

  • Immunity+ Evidence Growing

  • The 3000 Cow High Immune Response (HIR) Genomics Project

  • Prevalence Of Digital Dermatitis In Canadian Dairy Cattle Classified As High, Average Of Low Antibody And Cell-Mediated Immune Responders

  • Breeding Cows With Superior Immune Response

  • Profiting From Genetic Disease Resistance

  • Breeding Your Cows For High Immune Response Can Result In A Herd Less Prone To Mastitis

  • Dairy Farmers Have A New Tool To Help Them Build A Healthier Herd

  • We Can Now Find The Best Immune Systems

  • Genetic And Epigenetic Regulation Of Immune Response And Resistance To Infectious Diseases In Domestic Ruminants

  • A Genome-Wide Association Study For Natural Antibodies Measured In Blood Of Canadian Holstein Cows

  • Variation Of Total Immunoglobulin G And β-Lactoglobulin Concentrations In Colostrum And Milk From Canadian Holsteins Classified As High, Average, Or Low Immune Responders

  • High Immune Response Sires Reduce Disease Incidence In North American Large Commercial Dairy Populations

  • Variation In Production Parameters Among Canadian Holstein Cows Classified As High, Average, And Low Immune Responders

  • Association Of Disease Incidence And Adaptive Immune Response In Holstein Dairy Cows

  • Genetic Parameters Of Adaptive Immune Response Traits In Canadian Holsteins

  • A Genome-wide Association Study Of Immune Response Traits In Canadian Holstein Cattle

  • Bovine Mastitis: Frontiers In Immunogenetics

  • Incidence Rates Of Clinical Mastitis Among Canadian Holsteins Classified As High, Average, Or Low Immune Responders

  • Genetic Parameters For Natural Antibodies And Associations With Specific Antibody And Mastitis In Canadian Holsteins


  • DISEASES
    BIRD FLU – H5N1
    BOVINE LEUKOSIS
    BOVINE TUBERCULOSIS
    CALF DIARRHEA/SCOURS
    DIGITAL DERMATITIS
    DISPLACED ABOMASUM
    ENDOMETRITIS/METRITIS
    INTERDIGITAL HYPERPLASIA
    JOHNE'S DISEASE
    KETOSIS
    MASTITIS
    PNEUMONIA
    RETAINED PLACENTA

    IMMUNITY TECHNOLOGY
    Only from Semex Elevate® and Neogen®