Stronger Cows. Healthier Herds. More Profit.
Backed by over 25 years of research at the University of Guelph, Immunity Technology is a world-leading genetic solution that helps you breed cows with naturally stronger immune systems.

  • Healthier cows with fewer cases of mastitis, metritis, and respiratory disease
  • Lower vet and treatment costs
  • Improved fertility and longevity, keeping cows in your herd longer
  • More profit, with gains that build every generation
    By monitoring immunity in your herd, you’re not just treating disease — you’re preventing it.

  • ENDOMETRITIS/METRITIS

    Immunity+® & Endometritis/Metritis
    Endometritis — a postpartum uterine infection — is a common and economically costly disease in dairy cows, especially when it becomes clinical (visible discharge) or subclinical (detected only via exam or tests).

    Estimated Cost of Endometritis per Case:
    $110 to $350+ per affected cow
    Costs come mostly from reproductive losses (not treatment)
    Incidence rate typically 15–30% of cows after calving

    How Immunity+ Helps Fight Endometritis
    • Stronger Immune Defense Post-Calving
      • The postpartum period suppresses the cow’s immune system.
      • Immunity+ cows are better able to mount an effective immune response during this time.
      • This helps clear bacterial infections in the uterus more efficiently, reducing the risk of metritis and endometritis.
    • Better Control of Inflammation
      • Effective Immunity+ is not just about fighting pathogens — it’s about resolving inflammation properly.
      • Immunity+ cows are more likely to have balanced immune responses, avoiding:
        • Excessive inflammation (which delays uterine healing)
        • Inadequate response (which allows infection to persist)
    • Reduced Incidence of Associated Diseases
      • Diseases like retained placenta, mastitis, and ketosis are risk factors for metritis.
      • Immunity+ cows have lower rates of these diseases, thereby indirectly reducing the risks of metritis and endometritis.
    • Heritable Benefit for Future Generations
      • The high-immune-response trait is passed on to daughters.
      • This builds long-term herd resistance to uterine infections and other costly diseases.

    Summary: Semex’s Immunity+ helps fight metritis and endometritis by building a genetically stronger, more resilient immune system in dairy cows — leading to healthier uterine recovery, fewer infections, and improved reproductive performance.

    FIND OUT MORE
  • Immune Classification And Colostral Quality

  • Genetic Selection Of Cattle For Improved Immunity And Health

  • Breeding Your Cows For High Immune Response Can Result In A Herd Less Prone To Mastitis

  • We Can Now Find The Best Immune Systems

  • Breeding Cows with Superior Immune Response

  • Profiting From Genetic Disease Resistance

  • Dairy Farmers Have A New Tool To Help Them Build A Healthier Herd

  • Immunity+ Evidence Growing

  • Prevalence Of Digital Dermatitis In Canadian Dairy Cattle Classified As High, Average Of Low Antibody And Cell-Mediated Immune Responders

  • The 3000 Cow High Immune Response (HIR) Genomics Project

  • Genetic Selection Of Cattle For Improved Immunity And Health

  • Variation Of Lactoferrin And Total Immunoglobulin G Concentrations In Colostrum From Canadian Holstein Dairy Cattle Classified As High, Average Or Low Immune Responders

  • Genetic And Epigenetic Regulation Of The Bovine Immune System: Practical Implications Of The High Immune Response Technology

  • Are There Reproductive Implications When Dairy Cattle Are Genetically Selected For Improved Immunity?

  • Genetic Regulation Of The Bovine Immune System And The Practical Application Of The High Immune Response Technology In Dairy Health Management

  • The Use Of High Immune Response Bulls In A Herd

  • A Genome-wide Association Study Of Immune Response In Holstein Bulls

  • Genetic And Epigenetic Effects On Bovine Immune Responses And Their Implications To Dairy Health

  • Genetic Selection Of Cattle For Improved Immunity And Health

  • Prevalence Of Digital Dermatitis In Canadian Dairy Cattle Classified As High, Average Of Low Antibody And Cell-Mediated Immune Responders

  • A Genome-Wide Association Study For Natural Antibodies Measured In Blood Of Canadian Holstein Cows

  • High Immune Response Sires Reduce Disease Incidence In North American Large Commercial Dairy Populations

  • Incidence Rates Of Clinical Mastitis Among Canadian Holsteins Classified As High, Average, Or Low Immune Responders

  • Association Of Disease Incidence And Adaptive Immune Response In Holstein Dairy Cows

  • Bovine Mastitis: Frontiers In Immunogenetics

  • Genetic Parameters For Natural Antibodies And Associations With Specific Antibody And Mastitis In Canadian Holsteins

  • Genetic And Epigenetic Regulation Of Immune Response And Resistance To Infectious Diseases In Domestic Ruminants

  • Variation Of Total Immunoglobulin G And β-Lactoglobulin Concentrations In Colostrum And Milk From Canadian Holsteins Classified As High, Average, Or Low Immune Responders

  • Genetic Selection Of Cattle For Improved Immunity And Health

  • Variation In Production Parameters Among Canadian Holstein Cows Classified As High, Average, And Low Immune Responders

  • Genetic Parameters Of Adaptive Immune Response Traits In Canadian Holsteins

  • A Genome-wide Association Study Of Immune Response Traits In Canadian Holstein Cattle


  • DISEASES
    BIRD FLU – H5N1
    BOVINE LEUKOSIS
    BOVINE TUBERCULOSIS
    CALF DIARRHEA/SCOURS
    DIGITAL DERMATITIS
    DISPLACED ABOMASUM
    ENDOMETRITIS/METRITIS
    INTERDIGITAL HYPERPLASIA
    JOHNE'S DISEASE
    KETOSIS
    MASTITIS
    PNEUMONIA
    RETAINED PLACENTA

    IMMUNITY TECHNOLOGY
    Only from Semex Elevate® and Neogen®